UKPDS Outcomes Model - Isis Project No 2284

Oxford software to assess the lifetime benefits of diabetes-related interventions.

The Oxford Software

The UKPDS Outcomes Model is a computer simulation program developed jointly by the Diabetes Trials Unit in the Oxford Centre for Diabetes, Endocrinology and Metabolism and the Health Economics Research Centre in the University of Oxford Department of Public Health. The software is used for estimating the long-term impact of health interventions for people with type 2 diabetes. The model is based on patient data from the United Kingdom Prospective Diabetes Study and is designed to assess the total burden of disease over an extrapolated lifetime for populations with type 2 diabetes. The model uses a wide variety of risk factors such as blood glucose level, blood pressure, lipid levels and smoking status, including knowledge of previous events for individuals, and has the ability to take into account changes in risk factor levels over time.

Applications

The software has been developed primarily to assess the lifetime benefits of diabetes-related interventions. In particular, it is intended to facilitate economic evaluations by estimating changes in life expectancy and quality-adjusted life expectancy for each member of a given population when risk factors are changed. It can be applied to any population with type 2 diabetes. Other potential applications include:

• Assisting health service planning for populations with diabetes
• Estimating life expectancy for life insurance premium calculations
• Calculating expected event rates when designing clinical trials.

Software Status

The UKPDS Outcomes Model software is being used in a range of research, clinical and commercial applications worldwide. The software is available for commercial and academic use in the form of a standalone application for Microsoft, Macintosh and Linux platforms. An Excel worksheet version is available on Microsoft Windows.

A licence to use the software developed at Oxford can be obtained by completing the online licence request form »

To review academic use licence terms, please visit http://www.dtu.ox.ac.uk.

 

Request Further Information: Project Number 2284 - Health Economics Software Product